Thursday, January 23, 2025
6:00 - 7:00 pm, Registration
7:00 - 7:10 pm, Opening Remarks
7:10 - 8:00 pm, Keynote Lecture, Robert Tampé (Goethe University/Institute of Biochemistry), "Illuminating Cellular Machineries in Adaptive Immunity"
8:00 - 10:00 pm, Reception
Friday, January 24, 2025
8:20 - 10:15 am, Methods: Antibody and Antigen Covalent Structure Characterization (de Novo Sequencing, Glycosylation, Other PTMs) 1
- Neil Kelleher (Northwestern University), "From Antibody-Based Drugs to Ultra-precise Serology Readouts at Single Clone Resolution"
- Parastoo Azadi (Complex Carbohydrate Research Center, U. of Georgia)
- Roman Zubarev (Karolinska Inst.), "SpotLight Proteomics for Identification of Disease-Specific Antibody Sequences"
- Shunhai Wang (Regeneron Pharmaceuticals) "Study the Impact of mAb PTMs on Target and Fc Receptor Binding by Affinity-Resolved SEC-MS"
- Contributed Talks from Abstract Submissions
10:15 - 10:35 am, Coffee Break
10:35 am - 12:05 pm, Applications: Immunopeptidomics
- Jennifer Abelin (Broad Institute), "Sensitive Detection of HLA Presented Antigens via User-Defined Peptide Spectral Libraries"
- Pierre Thibault (University of Montreal), "Hidden Tumor Antigens in Colorectal Cancer: A Proteogenomic Path to Vaccines"
- Nicola Ternette (University of Dundee, Scotland), "Immune-Recognition Of Antibody Drugs"
- Contributed Talks from Abstract Submissions
12:05 - 1:00 pm, Lunch (provided by ASMS) and Group Photo
1:00 - 2:30 pm, Methods & Applications: Characterization of Polyclonal Antibodies and Antibodies beyond the γ Isotype
- Keynote speaker: Albert Heck (Utrecht University, Netherlands), "On the Structural and Clonal Peculiarities of IgA and IgM"
- Jiwon Lee (Dartmouth College)
- David L. Murray (Mayo Clinic), "Bringing Mass Spectrometry into the Care of Patients with Myeloma"
- Contributed Talks from Abstract Submissions
2:30 - 2:50 pm, Coffee Break
2:50 - 3:55 pm, Methods: Higher Order Structure 1 (HDX, OxidativeLlabeling/FPOP, Other Chemical Labeling Methods, Chemical Cross-Linking and LimitedPproteolysis – Focus on Epitope/Paratope Mapping)
- Keynote speaker: Michael L. Gross (Washington University), "What do MS Methods Teach us about Antigens?"
- Michael Glocker (Universität Rostock), "Intact Transition Epitope Mapping (ITEM)"
- Contributed Talk from Abstract Submissions
3:55 - 7:00 pm, Free Time
7:00 - 9:00 pm, Poster Session I
Saturday, January 25, 2025
8:20 - 9:50 am, Applications: OMICS and Bioinformatics in Immunology 1 (Adaptive and Innate Immune Signaling - Focus on Proteomics)
- Chris Overall (University of British Columbia)
- Bryan Bryson (MIT)
- Aleksandra Nita-Lazar (NIAID), "Signaling Mechanisms and Protein Networks in Innate Immunity"
- Contributed Talks From Abstract Submissions
9:50 - 10:10 am, Coffee Break
10:10 - 11:15 am, Applications: OMICS and Bioinformatics in Immunology 2 (Immune Signaling and Responses - Focus on Lipids and Small Molecules)
- Alison Scott (University of Maryland), "Identification of Novel Mechanistic Targets in Pulmonary Infection Models Using Spatial Lipidomics"
- Jennifer Brodbelt (University of Texas)
- Contributed Talk from Abstract Submissions
11:15 am - 7:00 pm, Free Time
7:00 - 9:00 pm, Poster Session II
Sunday, January 26, 2025
8:20 - 9:40 am, Methods: Higher Order Structure 2 (Native MS in Immunology)
- David Clemmer (Megadalton Solutions/Univ. Indiana Bloomington)
- Guanbo Wang (Peking University, China, Biomedical Pioneering Innovation Center), "Resolving the Structural Heterogeneity of Natural Protein Complexes and Recombinant Protein Vaccines by Native MS"
- Contributed Talks from Abstract Submissions
9:40 - 10:00 am, Coffee Break
10:00 - 11:40 am, Applications: Autoimmunity, Allergy and Anaphylaxis
- Cheryl Lichti (Washington University)
- Wenhua Yang (Zhongkai University of Agriculture and Engineering), "Characterization of Ovalbumin and Its Monoclonal IgE by Mass Spectrometry"
- Igor Kaltashov (UMass-Amherst), "Understanding the Mechanism of an Adenoviral-Vectored Vaccine Side Effect by Reverse-Engineering of the Pathogenic Antibody"
- Elena Dominguez-Vega (Leiden Univ. Medical Center), "Discriminating Autoimmune Responses in Rheumatoid Arthritis: Autoantibody Fc-Proteoforms and their Association with Disease Activity"
11:40 am - 12:40 pm, Lunch, on your own
12:40 - 2:20 pm, Applications: Host-Pathogen Interactions
- Ileana Cristea (Princeton University)
- Jennifer Geddes-McAlister (Guelph University), "Dual Perspective Proteome Remodeling of Fungal Infections"
- Boris Macek (University of Tuebingen), "Post-Translational Regulation of Bacterial Stress Response: Focus on Ser/Thr Kinases"
- Robert Ernst (Univ. of Maryland College Park)
2:20 - 2:40 pm, Coffee Break
2:40 - 3:45 pm, Closing Plenary and Remarks
Optional Departures Depending upon Flights.
Monday, January 27, 2025
Departures at Leisure