Ying Ge, 2020 Recipient
Dr. Ying Ge is the recipient of the 2020 Biemann Medal for significant contributions to high-resolution mass spectrometry (MS)-based top-down proteomics and their application to cardiac diseases. Dr. Ge has demonstrated that Fourier transform ion cyclotron resonance (FT-ICR) MS with electron capture dissociation (ECD) is especially useful for mapping labile post-translational modifications, and she has isotopically resolved large proteins with high mass accuracy, allowing the characterization of very large proteins directly from human heart tissues.
To address the many challenges in top-down proteomics, she has successfully developed novel strategies for protein extraction, solubility, and separation to enable comprehensive top-down MS characterization of biologically critical cardiac proteins. Her technical excellence has allowed her to make important discoveries in myofilament biology and gain novel insights into the understanding of cardiac diseases. For example, she has identified phosphorylation of cardiac troponin I and actin isoform switching as potential biomarkers for chronic heart failure by top-down MS. Dr. Ge’s significant contributions to both MS-based top-down proteomics and her fundamental insights into cardiac pathologies make her an outstanding recipient of the Biemann Medal.
Dr. Ge is Professor of Cell and Regenerative Biology and Chemistry at the University of Wisconsin at Madison.
The Biemann Medal recognizes significant achievement made in the early stages of a career.
Nominations are due November 30. Nomination Form (PDF fill-in form). The Biemann Medal is awarded to an individual early in his or her career in recognition of significant achievement in basic or applied mass spectrometry. The Biemann Medal was established by contributions from students, postdoctoral associates and friends to honor Professor Klaus Biemann.
- Nominees must be within the first 15 years of receiving the Ph.D. in the year nomination is considered. This is a general guideline and exceptions will be considered. Exceptions should be requested in the letter of nomination.
- Eligibility is restricted to members of ASMS.
Nominations are held for three years so long as the date of PhD is still within the eligible range. The award is conferred at the ASMS Annual Conference with the presentation of a $5,000 cash award, the Biemann Medal, and the award lecture.