About the Sanibel Conference 2020
Exposomics is the application of omics methodologies to characterize and quantify the exposome. The exposome not only compromises all human exposures from birth to death but it also compliments the genome and integrates non-genetic exposures with associated biological response pathways in the search for causative factors of chronic human disease. Comprehensive characterization of all chemical exposures in the human internal and external environment is the main objective of the exposome. Within the exposome paradigm, the internal environment is composed of all bio-active chemicals circulating in the body. These include but are not limited to, dietary compounds, persistent environmental pollutants, xenobiotics, pharmaceuticals, metabolites and chemicals and signaling molecules synthesized by the external and internal microbiota (collectively referred to as the microbiome) all humans host. The external environment is composed of all potential exposures ranging from near-field to far-field sources of exogenous chemicals and uses both computational and experimental approaches to associate risk to these exposures leading to a holistic view of the exposome, essentially mapping the chemical space of the world around and inside of humans.
The conference will bring together experts in the fields of exposomics, metabolomics, microbiome research, epidemiology, systems biology and bioinformatics from government, industry and academia. Discussions will include the current status and trends in MS characterization of the exposome and the microbiome with the focus on qualitative and quantitative analyses using targeted, semi-targeted and discovery-based/non-targeted methodologies.