Lan Huang
University of California, Irvine
Candidate Statement
As a long-standing member of ASMS, I have experienced the immense value this society brings, not only in advancing scientific knowledge but also in fostering collaboration and professional development. ASMS has been instrumental in my professional life throughout my career. It would be a great honor to serve the society that I care so deeply about. I am eager to serve as Member-at-Large for Publications and help promote inclusivity, innovation, and excellence in ASMS publications. In addition, I would like to help provide a variety of educational resources to support the professional growth of all society members and contribute to the continued success of ASMS.
Lan Huang, Ph.D. in Analytical Chemistry, University of Florida. Professor of Physiology & Biophysics and Director of High-End Mass Spectrometry Facility in School of Medicine, University of California, Irvine (UCI). She has been a faculty member at UCI since 2003.
Dr. Huang’s research focuses on developing integrated mass spectrometry-based proteomics strategies to characterize macromolecular machines and understand their functions. During the last two decades, the Huang lab has developed a number of novel methodologies to study protein-protein interactions in living cells. She has pioneered the development of sulfoxide-containing MS-cleavable cross-linkers to establish a robust cross-linking mass spectrometry platform, enabling the elucidation of interaction networks and structural topologies of native proteomes in vitro and in vivo. The strategies developed by her group have proven highly effective as general proteomics tools for studying protein-protein interactions and protein complexes. Additionally, her research has contributed significantly to the understanding of protein ubiquitination and degradation. She has successfully translated her research findings into practical applications, receiving several patents and commercializing reagents that have made a substantial impact in the scientific community. Her work has resulted in 165 peer-reviewed papers.
Beyond her research, Dr. Huang has been intensely involved in serving the mass spectrometry and proteomics communities. She has been serving on various committees for multiple organizations including ASMS, ASBMB, US HUPO, and CASMS, and as the President of CASMS (2021-2023). In particular, she has served on multiple ASMS committees including publication, research award, and nominating committees. In addition, she has served as a co-leader of an ASMS interest group, chaired several ASMS conference sessions, and co-organized the Sanibel conference on “Chemical Cross-linking and Covalent Labeling”. Moreover, she has served as an ad hoc reviewer, a standing member, and chair of NIH study sections, as well as an ad hoc reviewer for numerous journals. Dr. Huang currently serves as an Associate Editor for both Molecular & Cellular Proteomics and FASEB BioAdvances.