John R. Yates III
Scripps Research Institute
Candidate Statement
ASMS has been at the heart of my scientific life, shaping my career and surrounding me with a community of colleagues and friends. Every annual meeting renews my excitement for mass spectrometry, from the thrill of new discoveries to the joy of talking with the next generation of scientists. I am genuinely enthusiastic about the opportunity to serve as Vice President for Programs, where I can help ensure that ASMS meetings remain the vibrant, welcoming, and inspiring events that have meant so much to me and to so many others in our field.
Dr. John R. Yates III’s research focuses on advancing methods for tandem mass spectrometry and applying them to complex biological systems. He is the lead inventor of SEQUEST, the algorithm for correlating tandem MS data with protein sequences, and the developer of the shotgun proteomics strategy that enabled large-scale analysis of protein mixtures using both data-dependent (DDA) and data-independent (DIA) acquisition. His laboratory continues to innovate in the application of proteomics to study protein complexes, post-translational modifications, organelles, and quantitative protein expression, driving discoveries in basic and translational biology. More recently, his group is exploring the three-dimensional proteome and its implications for disease biology and clinical applications.
Dr. Yates has been an active member of the American Society for Mass Spectrometry (ASMS) since attending his first conference in 1983. He has organized and chaired numerous sessions, served on the program committee, participated in several ad hoc committees for the ASMS Board, and served as a Board Member-at-Large for Digital Communications. His leadership extends to related scientific organizations; he has organized two US HUPO and two international HUPO (iHUPO) conferences, served as Treasurer and President of US HUPO, and sat on the boards of the iHUPO and HPLC organizations. He has also served on standing and ad hoc committees for the ACS.
Beyond professional societies, Dr. Yates has contributed extensively to the broader scientific community. Since 2010, he has served on the Scientific Advisory Board of the Partnership for Clean Competition, guiding anti-doping research initiatives. He served on and chaired the NIH EBIT study section, he has participated in numerous NIH review panels, and he was a long-time reviewer for Genome Canada and a member of their SAIC board for 6 years. He served for 15 years as Associate Editor of Analytical Chemistry and for the past nine years as Editor-in-Chief of the Journal of Proteome Research. He has participated as a mentor for early-career researcher groups at US HUPO and iHUPO. In summary, Dr. Yates brings exceptional leadership experience and enthusiasm to the ASMS community—qualities that will help sustain the Society’s vibrancy, inclusivity, and global impact.