2010 Fall Workshop:  Glycoproteomics and Glycomics

Thursday Nov. 4	Friday Nov. 5	Saturday Nov. 6	Sunday Nov. 7	Sunday through Wednesday Nov. 7 - 10
Arrive at leisure	9:00 am - 12:00 pm Session A	9:00 - 12:00 Session C	Depart at leisure (or stay on for the Conference on Glycobiology)	Conference on Glycobiology For details and to register, go to: http://www.glycobiology.org
	12:00 - 1:00 pm Workshop Lunch	12:00 - 1:00 pm Workshop Lunch
	1:00 - 5:00 pm Session B	1:00 - 5:00 pm Session D
	Evening Dinner on own	Evening Dinner on own

 

Glycan expression is required for normal development and for functioning of all physiological system. Mass spectrometry methods are emerging as the most effective means for glycan identification, structural determination and quantification. Effective uses of mass spectrometry underlie basic studies of glycoconjugate function, drug target identification, biomarker identification, and glycoprotein drug product development.

The Fall Workshop will occur in conjunction with the 2010 Annual Meeting of the Society for Glycobiology. The Workshop program will begin with an introduction to the roles of glycosylation in biology followed by a summary of general glyco-analytical and emerging chemical biology methods in glycomics. The presentations will emphasize the chemical and biochemical principles behind the effective uses of mass spectrometry for characterization of glycosylated molecules.

Attendees of this workshop will learn to apply modern biomolecular mass spectrometry techniques to glycosylated compounds. The most effective methods for tandem MS of glycans will be covered, including how to interpret glycan tandem mass spectra. Lectures will focus on glycoproteomics, and glycomics of β-O-GlcNAc, N-glycans, O-glycans, glycolipids, and glycosaminoglycans.

Preliminary list of speakers and topics
Introduction to glycobiology, Lance Wells, University of Georgia
Introduction to glycoanalytical methods, Joseph Zaia, Boston University
Chemical biology methods in glycomics, Linda Hsieh-Wilson, California Institute of Technology
Glycoprotein/biological drug product characterization, Parastoo Azadi, University of Georgia
MALDI MS based glycomics, Stuart Haslam, Imperial College
LC/MS based glycomics, Steve Levery, University of Copenhagen
Glycan tandem MS, Vernon Reinhold, University of New Hampshire
Software tools for glycoproteomics and glycomics, Stuart Haslam, Imperial College
Glycan site mapping, Lance Wells, University of Georgia
Glycomics of N- and O¬-glycans, quantitative methods, Ron Orlando, University of Georgia
Heparin and glycosaminoglycan methods, Joseph Zaia, Boston University
Glycomics of glycolipids, Steve Levery, University of Copenhagen
Summary and wrap-up